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Identification of genetic modifiers of age-at-onset for familial Parkinson’s disease
Parkinson’s disease (PD) is the most common cause of neurodegenerative movement disorder and the second most common cause of dementia. Genes are thought to have a stronger effect on age-at-onset of PD than on risk, yet there has been a phenomenal success in identifying risk loci but not age-at-onset...
Autores principales: | Hill-Burns, Erin M., Ross, Owen A., Wissemann, William T., Soto-Ortolaza, Alexandra I., Zareparsi, Sepideh, Siuda, Joanna, Lynch, Timothy, Wszolek, Zbigniew K., Silburn, Peter A., Mellick, George D., Ritz, Beate, Scherzer, Clemens R., Zabetian, Cyrus P., Factor, Stewart A., Breheny, Patrick J., Payami, Haydeh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216611/ https://www.ncbi.nlm.nih.gov/pubmed/27402877 http://dx.doi.org/10.1093/hmg/ddw206 |
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