Altered calcium influx of peripheral Th2 cells in pediatric Crohn's disease: infliximab may normalize activation patterns

OBJECTIVE: Crohn's disease is a chronic inflammation of the gastrointestinal tract with an abnormal immune phenotype. We investigated how intracellular calcium kinetics of Th1 and Th2 lymphocytes alter upon specific inhibition of Kv1.3 and IKCa1 channels in pediatric Crohn's disease. STUDY...

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Detalles Bibliográficos
Autores principales: Orbán, Csaba, Szabó, Dolóresz, Bajnok, Anna, Vásárhelyi, Barna, Tulassay, Tivadar, Arató, András, Veres, Gábor, Toldi, Gergely
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper: Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216698/
https://www.ncbi.nlm.nih.gov/pubmed/27329601
http://dx.doi.org/10.18632/oncotarget.10036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216698/
https://www.ncbi.nlm.nih.gov/pubmed/27329601
http://dx.doi.org/10.18632/oncotarget.10036

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