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Interaction of toxic and non-toxic HypF-N oligomers with lipid bilayers investigated at high resolution with atomic force microscopy

Protein misfolded oligomers are considered the most toxic species amongst those formed in the process of amyloid formation and the molecular basis of their toxicity, although not completely understood, is thought to originate from the interaction with the cellular membrane. Here, we sought to highli...

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Detalles Bibliográficos
Autores principales: Oropesa-Nuñez, Reinier, Seghezza, Silvia, Dante, Silvia, Diaspro, Alberto, Cascella, Roberta, Cecchi, Cristina, Stefani, Massimo, Chiti, Fabrizio, Canale, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216700/
https://www.ncbi.nlm.nih.gov/pubmed/27391440
http://dx.doi.org/10.18632/oncotarget.10449