EZH2 promotes metabolic reprogramming in glioblastomas through epigenetic repression of EAF2-HIF1α signaling

Cancer cells prefer glycolysis for energy metabolism, even when there is sufficient oxygen to make it unnecessary. This is called the Warburg effect, and it promotes tumorigenesis and malignant progression. In this study, we demonstrated that EZH2, a multifaceted oncogenic protein involved in tumor...

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Detalles Bibliográficos
Autores principales: Pang, Bo, Zheng, Xiang-Rong, Tian, Jing-xia, Gao, Tai-hong, Gu, Guang-yan, Zhang, Rui, Fu, Yi-Bing, Pang, Qi, Li, Xin-Gang, Liu, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216711/
https://www.ncbi.nlm.nih.gov/pubmed/27259264
http://dx.doi.org/10.18632/oncotarget.9761

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216711/
https://www.ncbi.nlm.nih.gov/pubmed/27259264
http://dx.doi.org/10.18632/oncotarget.9761

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