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EZH2 promotes metabolic reprogramming in glioblastomas through epigenetic repression of EAF2-HIF1α signaling
Cancer cells prefer glycolysis for energy metabolism, even when there is sufficient oxygen to make it unnecessary. This is called the Warburg effect, and it promotes tumorigenesis and malignant progression. In this study, we demonstrated that EZH2, a multifaceted oncogenic protein involved in tumor...
Autores principales: | Pang, Bo, Zheng, Xiang-Rong, Tian, Jing-xia, Gao, Tai-hong, Gu, Guang-yan, Zhang, Rui, Fu, Yi-Bing, Pang, Qi, Li, Xin-Gang, Liu, Qian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216711/ https://www.ncbi.nlm.nih.gov/pubmed/27259264 http://dx.doi.org/10.18632/oncotarget.9761 |
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