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Giant obscurins regulate the PI3K cascade in breast epithelial cells via direct binding to the PI3K/p85 regulatory subunit

Obscurins are a family of giant cytoskeletal proteins, originally identified in striated muscles where they have structural and regulatory roles. We recently showed that obscurins are abundantly expressed in normal breast epithelial cells where they play tumor and metastasis suppressing roles, but a...

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Detalles Bibliográficos
Autores principales:	Shriver, Marey, Marimuthu, Saravanakumar, Paul, Colin, Geist, Janelle, Seale, Tessa, Konstantopoulos, Konstantinos, Kontrogianni-Konstantopoulos, Aikaterini
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216731/ https://www.ncbi.nlm.nih.gov/pubmed/27323778 http://dx.doi.org/10.18632/oncotarget.9985

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