The metabolic/pH sensor soluble adenylyl cyclase is a tumor suppressor protein

cAMP signaling pathways can both stimulate and inhibit the development of cancer; however, the sources of cAMP important for tumorigenesis remain poorly understood. Soluble adenylyl cyclase (sAC) is a non-canonical, evolutionarily conserved, nutrient- and pH-sensing source of cAMP. sAC has been impl...

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Detalles Bibliográficos
Autores principales: Ramos-Espiritu, Lavoisier, Diaz, Ana, Nardin, Charlee, Saviola, Anthony J., Shaw, Fiona, Plitt, Tamar, Yang, Xia, Wolchok, Jedd, Pirog, Edyta C., Desman, Garrett, Sboner, Andrea, Zhang, Tuo, Xiang, Jenny, Merghoub, Taha, Levin, Lonny R., Buck, Jochen, Zippin, Jonathan H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216745/
https://www.ncbi.nlm.nih.gov/pubmed/27323809
http://dx.doi.org/10.18632/oncotarget.10056

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