miR-26a desensitizes non-small cell lung cancer cells to tyrosine kinase inhibitors by targeting PTPN13

Epidermal growth factor receptor (EGFR)-targeted tyrosine kinase inhibitors (TKIs) have emerged as first-line drugs for non-small cell lung cancers (NSCLCs). However, the resistance to TKIs represents the key limitation for their therapeutic efficacy. We found that miR-26a was upregulated in gefitin...

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Detalles Bibliográficos
Autores principales: Xu, Shudi, Wang, Tao, Yang, Zhiwei, Li, Ying, Li, Weijie, Wang, Ting, Wang, Shan, Jia, Lintao, Zhang, Shengli, Li, Shengqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216753/
https://www.ncbi.nlm.nih.gov/pubmed/27285768
http://dx.doi.org/10.18632/oncotarget.9920

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216753/
https://www.ncbi.nlm.nih.gov/pubmed/27285768
http://dx.doi.org/10.18632/oncotarget.9920

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