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Characterization of RON protein isoforms in pancreatic cancer: implications for biology and therapeutics
The RON tyrosine kinase receptor is under investigation as a novel target in pancreatic cancer. While RON mutations are uncommon, RON isoforms are produced in cancer cells via a variety of mechanisms. In this study we sought to: 1) characterize RON isoform expression in pancreatic cancer, 2) investi...
Autores principales: | Chakedis, Jeffery, French, Randall, Babicky, Michele, Jaquish, Dawn, Mose, Evangeline, Cheng, Peter, Holman, Patrick, Howard, Haleigh, Miyamoto, Jaclyn, Porras, Paula, Walterscheid, Zakk, Schultz-Fademrecht, Carsten, Esdar, Christina, Schadt, Oliver, Eickhoff, Jan, Lowy, Andrew M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216774/ https://www.ncbi.nlm.nih.gov/pubmed/27323855 http://dx.doi.org/10.18632/oncotarget.10009 |
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