Cargando…

Methamphetamine-mediated endoplasmic reticulum (ER) stress induces type-1 programmed cell death in astrocytes via ATF6, IRE1α and PERK pathways

Methamphetamine (MA), a psychostimulant drug has been associated with a variety of neurotoxic effects which are thought to be mediated by induction of pro-inflammatory cytokines/chemokines, oxidative stress and damage to blood-brain-barrier. Conversely, the ER stress-mediated apoptosis has been impl...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shah, Ankit, Kumar, Anil
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216784/ https://www.ncbi.nlm.nih.gov/pubmed/27323860 http://dx.doi.org/10.18632/oncotarget.10025

Ejemplares similares

Dynamic changes in complexes of IRE1α, PERK, and ATF6α during endoplasmic reticulum stress
por: Sundaram, Arunkumar, et al.
Publicado: (2018)

PCV2 and PRV Coinfection Induces Endoplasmic Reticulum Stress via PERK-eIF2α-ATF4-CHOP and IRE1-XBP1-EDEM Pathways
por: Chen, Si, et al.
Publicado: (2022)

Endoplasmic Reticulum Stress Is Involved in Stress-Induced Hypothalamic Neuronal Injury in Rats via the PERK-ATF4-CHOP and IRE1-ASK1-JNK Pathways
por: Yi, Shanyong, et al.
Publicado: (2019)

Novel mechanism of enhancing IRE1α-XBP1 signalling via the PERK-ATF4 pathway
por: Tsuru, Akio, et al.
Publicado: (2016)

Induction of Endoplasmic Reticulum Stress Pathway by Green Tea Epigallocatechin-3-Gallate (EGCG) in Colorectal Cancer Cells: Activation of PERK/p-eIF2α/ATF4 and IRE1α
por: Md Nesran, Zarith Nameyrra, et al.
Publicado: (2019)

Endoplasmic Reticulum Stress in Colonic Mucosa of Ulcerative Colitis Patients Is Mediated by PERK and IRE1 Pathway Activation
por: Rodrigues, Bruno Lima, et al.
Publicado: (2022)

PARP16 is a tail-anchored endoplasmic reticulum protein required for the PERK and IRE1α-mediated unfolded protein response
por: Jwa, Miri, et al.
Publicado: (2012)

IRE1β negatively regulates IRE1α signaling in response to endoplasmic reticulum stress
por: Grey, Michael J., et al.
Publicado: (2020)

IRE1α is an endogenous substrate of endoplasmic reticulum-associated degradation
por: Sun, Shengyi, et al.
Publicado: (2015)

HIV-1 gp120 induces type-1 programmed cell death through ER stress employing IRE1α, JNK and AP-1 pathway
por: Shah, Ankit, et al.
Publicado: (2016)

Non-Structural Protein 2B of Human Rhinovirus 16 Activates Both PERK and ATF6 Rather Than IRE1 to Trigger ER Stress
por: Song, Juan, et al.
Publicado: (2019)

EGFR confers radioresistance in human oropharyngeal carcinoma by activating endoplasmic reticulum stress signaling PERK‐eIF2α‐GRP94 and IRE1α‐XBP1‐GRP78
por: Zhang, Miao, et al.
Publicado: (2018)

Dimethyl fumarate abrogates striatal endoplasmic reticulum stress in experimentally induced late-stage Huntington’s disease: Focus on the IRE1α/JNK and PERK/CHOP trajectories
por: Hassab, Lina Y., et al.
Publicado: (2023)

Endoplasmic Reticulum Stress Response Mediated by the PERK-eIF2α-ATF4 Pathway Is Involved in Osteoblast Differentiation Induced by BMP2
por: Saito, Atsushi, et al.
Publicado: (2011)

Knockdown of NUPR1 inhibits angiogenesis in lung cancer through IRE1/XBP1 and PERK/eIF2α/ATF4 signaling pathways
por: Wang, Lihuai, et al.
Publicado: (2023)

The eIF2 kinase PERK and the integrated stress response facilitate activation of ATF6 during endoplasmic reticulum stress
por: Teske, Brian F., et al.
Publicado: (2011)

Intense endoplasmic reticulum stress (ERS) / IRE1α enhanced Oxaliplatin efficacy by decreased ABCC10 in colorectal cancer cells
por: Liu, Xiaohui, et al.
Publicado: (2022)

Quercetin Affects Hsp70/IRE1α Mediated Protection from Death Induced by Endoplasmic Reticulum Stress
por: Storniolo, Antonello, et al.
Publicado: (2015)

PERK induces resistance to cell death elicited by endoplasmic reticulum stress and chemotherapy
por: Salaroglio, Iris C., et al.
Publicado: (2017)

IRE1α Implications in Endoplasmic Reticulum Stress-Mediated Development and Pathogenesis of Autoimmune Diseases
por: Junjappa, Raghu Patil, et al.
Publicado: (2018)

Endoplasmic Reticulum Stress PERK-ATF4-CHOP Pathway Is Associated with Hypothalamic Neuronal Injury in Different Durations of Stress in Rats
por: Yi, Shanyong, et al.
Publicado: (2017)

IMB-6G, a novel N-substituted sophoridinic acid derivative, induces endoplasmic reticulum stress-mediated apoptosis via activation of IRE1α and PERK signaling
por: Zhang, Na, et al.
Publicado: (2016)

IRE1α deficiency promotes tumor cell death and eIF2α degradation through PERK dipendent autophagy
por: Storniolo, Antonello, et al.
Publicado: (2018)

UPR proteins IRE1 and PERK switch BiP from chaperone to ER stress sensor
por: Kopp, Megan C, et al.
Publicado: (2019)

A Non-Canonical Role for IRE1α Links ER and Mitochondria as Key Regulators of Astrocyte Dysfunction: Implications in Methamphetamine use and HIV-Associated Neurocognitive Disorders
por: Proulx, Jessica, et al.
Publicado: (2022)

Loss of ATF6α in a human carcinoma cell line is compensated not by its paralogue ATF6β but by sustained activation of the IRE1 and PERK arms for tumor growth in nude mice
por: Jin, Shengyu, et al.
Publicado: (2023)

A critical role of DDRGK1 in endoplasmic reticulum homoeostasis via regulation of IRE1α stability
por: Liu, Jiang, et al.
Publicado: (2017)

A Molecular Mechanism for Turning Off IRE1α Signaling during Endoplasmic Reticulum Stress
por: Li, Xia, et al.
Publicado: (2020)

Decoding non-canonical mRNA decay by the endoplasmic-reticulum stress sensor IRE1α
por: Le Thomas, Adrien, et al.
Publicado: (2021)

CPNE1 regulates myogenesis through the PERK-eIF2α pathway mediated by endoplasmic reticulum stress
por: Chen, Lin, et al.
Publicado: (2022)

Fuziline alleviates isoproterenol‐induced myocardial injury by inhibiting ROS‐triggered endoplasmic reticulum stress via PERK/eIF2α/ATF4/Chop pathway
por: Fan, Cai‐lian, et al.
Publicado: (2019)

Correction to: IRE1α deficiency promotes tumor cell death and eIF2α degradation through PERK-dependent autophagy
por: Storniolo, Antonello, et al.
Publicado: (2018)

Ciclopirox activates PERK-dependent endoplasmic reticulum stress to drive cell death in colorectal cancer
por: Qi, Jianjun, et al.
Publicado: (2020)

ER Stress Activates NF-κB by Integrating Functions of Basal IKK Activity, IRE1 and PERK
por: Tam, Arvin B., et al.
Publicado: (2012)

TBHQ Alleviated Endoplasmic Reticulum Stress-Apoptosis and Oxidative Stress by PERK-Nrf2 Crosstalk in Methamphetamine-Induced Chronic Pulmonary Toxicity
por: Wang, Yun, et al.
Publicado: (2017)

Divergent Effects of PERK and IRE1 Signaling on Cell Viability
por: Lin, Jonathan H., et al.
Publicado: (2009)

Homeostatic adaptation to endoplasmic reticulum stress depends on Ire1 kinase activity
por: Rubio, Claudia, et al.
Publicado: (2011)

Valdecoxib Protects against Cell Apoptosis Induced by Endoplasmic Reticulum Stress via the Inhibition of PERK-ATF4-CHOP Pathway in Experimental Glaucoma
por: Gao, Zhaolin, et al.
Publicado: (2022)

Loss of STIM2 in colorectal cancer drives growth and metastasis through metabolic reprogramming and PERK-ATF4 endoplasmic reticulum stress pathway
por: Pathak, Trayambak, et al.
Publicado: (2023)

Geraniol-Mediated Suppression of Endoplasmic Reticulum Stress Protects against Cerebral Ischemia–Reperfusion Injury via the PERK-ATF4-CHOP Pathway
por: Wu, Yu, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_fdo1r7b1e1a05sdg67s0f19975