Chromatin remodeling gene AT-rich interactive domain-containing protein 1A suppresses gastric cancer cell proliferation by targeting PIK3CA and PDK1

The tumor suppressor gene AT-rich interactive domain-containing protein 1A (ARID1A) was frequently mutated in cancers. The modulation mechanism of ARID1A for PI3K/AKT signaling in gastric cancer (GC) remains elusive. Here, we found that depletion of endogenous ARID1A enhanced the in vitro proliferat...

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Detalles Bibliográficos
Autores principales: Zhang, Qian, Yan, Hai-Bo, Wang, Jie, Cui, Shu-Jian, Wang, Xiao-Qing, Jiang, Ying-Hua, Feng, Li, Yang, Peng-Yuan, Liu, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216786/
https://www.ncbi.nlm.nih.gov/pubmed/27323812
http://dx.doi.org/10.18632/oncotarget.10060

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