Cargando…

Deregulation of SOCS5 suppresses dendritic cell function in chronic lymphocytic leukemia

One cause of morbidity and mortality in chronic lymphocytic leukemia (CLL) is infection, which results from defects in a number of components of the immune system. In particular, dendritic cells (DCs) are functionally defective in patients with CLL. To understand the molecular mechanism for this abn...

Descripción completa

Detalles Bibliográficos
Autores principales:	Toniolo, Patricia A., Liu, Suhu, Yeh, Jennifer E., Ye, Darwin Q., Barbuto, José Alexandre M., Frank, David A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216799/ https://www.ncbi.nlm.nih.gov/pubmed/27317770 http://dx.doi.org/10.18632/oncotarget.10093

Ejemplares similares

Chronic lymphocytic leukemia-associated chromosomal abnormalities and miRNA deregulation
por: Kiefer, Yvonne, et al.
Publicado: (2012)

Dendritic Cell-Derived Exosomes may be a Tool for Cancer Immunotherapy by Converting Tumor Cells into Immunogenic Targets
por: Romagnoli, Graziela Gorete, et al.
Publicado: (2015)

Genomic deregulation of PRMT5 supports growth and stress tolerance in chronic lymphocytic leukemia
por: Schnormeier, Ann-Kathrin, et al.
Publicado: (2020)

Hsp90 inhibition increases SOCS3 transcript and regulates migration and cell death in chronic lymphocytic leukemia
por: Chen, Timothy L., et al.
Publicado: (2016)

T cell stimulation by dendritic cell-tumor cell hybrids is enhanced in the presence of free dendritic cells
por: Pinho, Mariana P, et al.
Publicado: (2013)

Curcumin Suppressed Activation of Dendritic Cells via JAK/STAT/SOCS Signal in Mice with Experimental Colitis
por: Zhao, Hai-Mei, et al.
Publicado: (2016)

miRNA-mediated deregulation in leukemia
por: Dell’Aversana, Carmela, et al.
Publicado: (2012)

RAS MAPK inhibitors deregulation in leukemia
por: Pasmant, Eric, et al.
Publicado: (2015)

Deregulation of the non-coding genome in leukemia
por: Teppo, Susanna, et al.
Publicado: (2017)

Functional loss of IκBε leads to NF-κB deregulation in aggressive chronic lymphocytic leukemia
por: Mansouri, Larry, et al.
Publicado: (2015)

Macroautophagy is deregulated in murine and human lupus T lymphocytes
por: Gros, Frédéric, et al.
Publicado: (2012)

Deregulation of PRDM5 promotes cell proliferation by regulating JAK/STAT signaling pathway through SOCS1 in human lung adenocarcinoma
por: Ren, Yuanyuan, et al.
Publicado: (2022)

Cytokine-driven loss of plasmacytoid dendritic cell function in chronic lymphocytic leukemia
por: Saulep-Easton, Damien, et al.
Publicado: (2014)

Oncogenic Deregulation of Cell Adhesion Molecules in Leukemia
por: Windisch, Roland, et al.
Publicado: (2019)

SOCS1: phosphorylation, dimerization and tumor suppression
por: Lessard, Frédéric, et al.
Publicado: (2019)

Regulation of Macrophage, Dendritic Cell, and Microglial Phenotype and Function by the SOCS Proteins
por: McCormick, Sarah M., et al.
Publicado: (2015)

Deregulation of calcium homeostasis in Bcr-Abl-dependent chronic myeloid leukemia
por: Cabanas, Hélène, et al.
Publicado: (2018)

The regulation of tumor‐suppressive microRNA, miR‐126, in chronic lymphocytic leukemia
por: Guinn, Daphne, et al.
Publicado: (2017)

The Emerging Role of Suppressors of Cytokine Signaling (SOCS) in the Development and Progression of Leukemia
por: Keewan, Esra’a, et al.
Publicado: (2021)

FXR induces SOCS3 and suppresses hepatocellular carcinoma
por: Guo, Fei, et al.
Publicado: (2015)

Enhanced induction of HIV-specific CTL by dendritic cell-targeted delivery of SOCS-1 siRNA
por: Subramanya, Sandesh, et al.
Publicado: (2010)

IL-1β Induces SOCS2 Expression in Human Dendritic Cells
por: Sarajlic, Muamera, et al.
Publicado: (2019)

The STAT3 Target Gene TNFRSF1A Modulates the NF-κB Pathway in Breast Cancer Cells()
por: Egusquiaguirre, Susana P., et al.
Publicado: (2018)

Effects of valproic acid on SOCS-1, SOCS-2, SOCS-3, SOCS-5, SOCS6, and SOCS-7 gene expression and cell growth inhibition in colon carcinoma
por: Sanaei, Masumeh, et al.
Publicado: (2022)

Management of relapsed/refractory Chronic Lymphocytic Leukemia
por: Woyach, Jennifer A.
Publicado: (2022)

Lymphocytes as Liver Damage Mirror of HCV Related Adipogenesis Deregulation
por: Minutolo, Antonella, et al.
Publicado: (2014)

SOCS1 Mimetic Peptide Suppresses Chronic Intraocular Inflammatory Disease (Uveitis)
por: He, Chang, et al.
Publicado: (2016)

Clonally related Histiocytic/dendritic cell sarcoma and chronic lymphocytic leukemia/small lymphocytic lymphoma: A study of 7 cases
por: Shao, Haipeng, et al.
Publicado: (2011)

JAK2-STAT5 signaling: A novel mechanism of resistance to targeted PI3K/mTOR inhibition
por: Yeh, Jennifer E, et al.
Publicado: (2013)

Decreased deformability of lymphocytes in chronic lymphocytic leukemia
por: Zheng, Yi, et al.
Publicado: (2015)

Deregulated WNT signaling in childhood T-cell acute lymphoblastic leukemia
por: Ng, O H, et al.
Publicado: (2014)

Mechanisms underlying transcription factor deregulation in acute lymphoblastic leukemia
por: Cools, Jan
Publicado: (2018)

SOCS2 Influences LPS Induced Human Monocyte-Derived Dendritic Cell Maturation
por: Hu, Jin, et al.
Publicado: (2009)

Immune system deregulation in hypertensive patients chronically RAS suppressed developing albuminuria
por: Martin-Lorenzo, Marta, et al.
Publicado: (2017)

Commentary: Soluble CD83 Alleviates Experimental Autoimmune Uveitis by Inhibiting Filamentous Actin-Dependent Calcium Release in Dendritic Cells
por: Pinho, Mariana Pereira, et al.
Publicado: (2018)

Alemtuzumab in chronic lymphocytic leukemia
por: Fraser, G., et al.
Publicado: (2007)

Chronic Lymphocytic Leukemia
por: Vaisitti, Tiziana, et al.
Publicado: (2020)

Chronic lymphocytic leukemia
por: Rossi, Davide
Publicado: (2018)

Suppression of CXCL-1 Could Restore Necroptotic Pathway in Chronic Lymphocytic Leukemia
por: Xu, Zhao, et al.
Publicado: (2020)

Transcriptional down-regulation of suppressor of cytokine signaling (SOCS)-3 in chronic obstructive pulmonary disease
por: Springer, Jochen, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_3pj6ao9ndtj71pavjqd0c8sc4n