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RRD-251 enhances all-trans retinoic acid (RA)-induced differentiation of HL-60 myeloblastic leukemia cells

All-trans-retinoic acid (RA) is known to induce terminal granulocytic differentiation and cell cycle arrest of HL-60 cells. Responding to an RA-induced cytosolic signaling machine, c-Raf translocates to the nucleus, providing propulsion for RA-induced differentiation. This novel mechanism is not und...

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Detalles Bibliográficos
Autores principales:	Wallace, Aaron S., Supnick, Harrison T., Bunaciu, Rodica P., Yen, Andrew
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216806/ https://www.ncbi.nlm.nih.gov/pubmed/27331409 http://dx.doi.org/10.18632/oncotarget.10136

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