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Metabolomics profiles delineate uridine deficiency contributes to mitochondria-mediated apoptosis induced by celastrol in human acute promyelocytic leukemia cells

Celastrol, extracted from “Thunder of God Vine”, is a promising anti-cancer natural product. However, its effect on acute promyelocytic leukemia (APL) and underlying molecular mechanism are poorly understood. The purpose of this study was to explore its effect on APL and underlying mechanism based o...

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Detalles Bibliográficos
Autores principales:	Zhang, Xiaoling, Yang, Jing, Chen, Minjian, Li, Lei, Huan, Fei, Li, Aiping, Liu, Yanqing, Xia, Yankai, Duan, Jin-ao, Ma, Shiping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216817/ https://www.ncbi.nlm.nih.gov/pubmed/27374097 http://dx.doi.org/10.18632/oncotarget.10286

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