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ERK1/2/MAPK pathway-dependent regulation of the telomeric factor TRF2

Telomere stability is a hallmark of immortalized cells, including cancer cells. While the telomere length is maintained in most cases by the telomerase, the activity of a protein complex called Shelterin is required to protect telomeres against unsuitable activation of the DNA damage response pathwa...

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Detalles Bibliográficos
Autores principales:	Picco, Vincent, Coste, Isabelle, Giraud-Panis, Marie-Josèphe, Renno, Toufic, Gilson, Eric, Pagès, Gilles
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216822/ https://www.ncbi.nlm.nih.gov/pubmed/27366950 http://dx.doi.org/10.18632/oncotarget.10316

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