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Deletion of 14-3-3σ sensitizes mice to DMBA/TPA-induced papillomatosis

The p53-inducible cell cycle regulator 14-3-3σ exhibits tumor suppressive functions and is highly expressed in differentiating layers of the epidermis and hair follicles. 14-3-3σ/SFN/stratifin is frequently silenced in human epithelial cancers, and experimental down-regulation of 14-3-3σ expression...

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Detalles Bibliográficos
Autores principales:	Winter, Markus, Lodygin, Dmitri, Verdoodt, Berlinda, Hermeking, Heiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Priority Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216908/ https://www.ncbi.nlm.nih.gov/pubmed/27409835 http://dx.doi.org/10.18632/oncotarget.10478

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