Human cytomegalovirus may promote tumour progression by upregulating arginase-2

BACKGROUND: Both arginase (ARG2) and human cytomegalovirus (HCMV) have been implicated in tumorigenesis. However, the role of ARG2 in the pathogenesis of glioblastoma (GBM) and the HCMV effects on ARG2 are unknown. We hypothesize that HCMV may contribute to tumorigenesis by increasing ARG2 expressio...

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Detalles Bibliográficos
Autores principales: Costa, Helena, Xu, Xinling, Overbeek, Gitta, Vasaikar, Suhas, Patro, C. Pawan K., Kostopoulou, Ourania N., Jung, Masany, Shafi, Gowhar, Ananthaseshan, Sharan, Tsipras, Giorgos, Davoudi, Belghis, Mohammad, Abdul-Aleem, Lam, Hoyin, Strååt, Klas, Wilhelmi, Vanessa, Shang, Mingmei, Tegner, Jesper, Tong, Joo Chuan, Wong, Kum Thong, Söderberg-Naucler, Cecilia, Yaiw, Koon-Chu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216936/
https://www.ncbi.nlm.nih.gov/pubmed/27363017
http://dx.doi.org/10.18632/oncotarget.9722

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