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LACE1 interacts with p53 and mediates its mitochondrial translocation and apoptosis

p53 is a major cellular tumor suppressor that in addition to its nuclear, transcription-dependent activity is also known to function extranuclearly. Cellular stressors such as reactive oxygen species can promote translocation of p53 into mitochondria where it acts to protect mitochondrial genome or...

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Detalles Bibliográficos
Autores principales: Cesnekova, Jana, Spacilova, Jana, Hansikova, Hana, Houstek, Josef, Zeman, Jiri, Stiburek, Lukas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216971/
https://www.ncbi.nlm.nih.gov/pubmed/27323408
http://dx.doi.org/10.18632/oncotarget.9959

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