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Hypoxia upregulates HIG2 expression and contributes to bevacizumab resistance in glioblastoma
Hypoxia contributes to the maintenance of stem-like cells in glioblastoma (GBM), and activates vascular mimicry and tumor resistance to anti-angiogenesis treatments. The present study examined the expression patterns and biological significance of hypoxia-inducible protein 2 (HIG2, also known as HIL...
Autores principales: | Mao, Xing-gang, Wang, Chao, Liu, Dong-ye, Zhang, Xiang, Wang, Liang, Yan, Ming, Zhang, Wei, Zhu, Jun, Li, Zi-chao, Mi, Chen, Tian, Jing-yang, Hou, Guang-dong, Miao, Si-yu, Song, Zi-xuan, Li, Jin-cheng, Xue, Xiao-yan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216980/ https://www.ncbi.nlm.nih.gov/pubmed/27329597 http://dx.doi.org/10.18632/oncotarget.10029 |
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