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RPL27A is a target of miR-595 and may contribute to the myelodysplastic phenotype through ribosomal dysgenesis
We investigated the functional consequences following deletion of a microRNA (miR) termed miR-595 which resides on chromosome 7q and is localised within one of the commonly deleted regions identified for Myelodysplasia (MDS) with monosomy 7 (−7)/isolated loss of 7q (7q-). We identified several targe...
Autores principales: | Alkhatabi, Heba A., McLornan, Donal P., Kulasekararaj, Austin G., Malik, Farooq, Seidl, Thomas, Darling, David, Gaken, Joop, Mufti, Ghulam J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216985/ https://www.ncbi.nlm.nih.gov/pubmed/27374104 http://dx.doi.org/10.18632/oncotarget.10293 |
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