Vitamin C uncouples the Warburg metabolic switch in KRAS mutant colon cancer

KRAS mutation is often present in many hard-to-treat tumors such as colon and pancreatic cancer and it is tightly linked to serious alterations in the normal cell metabolism and clinical resistance to chemotherapy. In 1931, the winner of the Nobel Prize in Medicine, Otto Warburg, stated that cancer...

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Detalles Bibliográficos
Autores principales: Aguilera, Oscar, Muñoz-Sagastibelza, María, Torrejón, Blanca, Borrero-Palacios, Aurea, del Puerto-Nevado, Laura, Martínez-Useros, Javier, Rodriguez-Remirez, María, Zazo, Sandra, García, Estela, Fraga, Mario, Rojo, Federico, García-Foncillas, Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216991/
https://www.ncbi.nlm.nih.gov/pubmed/27323830
http://dx.doi.org/10.18632/oncotarget.10087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216991/
https://www.ncbi.nlm.nih.gov/pubmed/27323830
http://dx.doi.org/10.18632/oncotarget.10087

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