Cargando…

FOXM1 promotes reprogramming of glucose metabolism in epithelial ovarian cancer cells via activation of GLUT1 and HK2 transcription

Cancer cells exhibit the reprogrammed metabolism mainly via aerobic glycolysis, a phenomenon known historically as the Warburg effect; however, the underlying mechanisms remain largely unknown. In this study, we characterized the critical role of transcription factor Forkhead box protein M1 (FOXM1)...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Yu, Yun, Yuyu, Wu, Bo, Wen, Li, Wen, Mingling, Yang, Huiling, Zhao, Lisheng, Liu, Wenchao, Huang, Suyun, Wen, Ning, Li, Yu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216994/ https://www.ncbi.nlm.nih.gov/pubmed/27351131 http://dx.doi.org/10.18632/oncotarget.10103

Ejemplares similares

FoxM1 promotes epithelial–mesenchymal transition, invasion, and migration of tongue squamous cell carcinoma cells through a c-Met/AKT-dependent positive feedback loop
por: Yang, Huiling, et al.
Publicado: (2018)

FOXM1 confers resistance to gefitinib in lung adenocarcinoma via a MET/AKT-dependent positive feedback loop
por: Wang, Yu, et al.
Publicado: (2016)

FOXM1 confers to epithelial-mesenchymal transition, stemness and chemoresistance in epithelial ovarian carcinoma cells
por: Chiu, Wen-Tai, et al.
Publicado: (2014)

Overexpression of FOXM1 predicts poor prognosis and promotes cancer cell proliferation, migration and invasion in epithelial ovarian cancer
por: Wen, Ning, et al.
Publicado: (2014)

Functional Analyse of GLUT1 and GLUT12 in Glucose Uptake in Goat Mammary Gland Epithelial Cells
por: Yu, Qinghua, et al.
Publicado: (2013)

Expression of Glut-1 and HK-II in Pancreatic Cancer and Their Impact on Prognosis and FDG Accumulation()
por: Yang, Hai-Jing, et al.
Publicado: (2016)

Roles of GLUT-1 and HK-II expression in the biological behavior of head and neck cancer
por: Yang, Hang, et al.
Publicado: (2019)

Peptide-based PROTAC degrader of FOXM1 suppresses cancer and decreases GLUT1 and PD-L1 expression
por: Wang, Kun, et al.
Publicado: (2022)

FOXM1 Modulates Cisplatin Sensitivity by Regulating EXO1 in Ovarian Cancer
por: Zhou, Jinhua, et al.
Publicado: (2014)

Expression of the glucose transporters GLUT1, GLUT3, GLUT4 and GLUT12 in human cancer cells
por: Barron, Carly, et al.
Publicado: (2012)

lncRNA GAS6-AS1 inhibits progression and glucose metabolism reprogramming in LUAD via repressing E2F1-mediated transcription of GLUT1
por: Luo, Jing, et al.
Publicado: (2021)

Placental expression of glucose transporters GLUT‐1, GLUT‐3, GLUT‐8 and GLUT‐12 in pregnancies complicated by gestational and type 1 diabetes mellitus
por: Stanirowski, Paweł Jan, et al.
Publicado: (2021)

Expression of GLUT1 and GLUT3 Glucose Transporters in Endometrial and Breast Cancers
por: Krzeslak, Anna, et al.
Publicado: (2012)

Effect of taxol on the expression of FoxM1 ovarian cancer-associated gene
por: LIU, ZENG, et al.
Publicado: (2016)

Prognostic Relevance of the Expression of CA IX, GLUT-1, and VEGF in Ovarian Epithelial Cancers
por: Kim, Kyungbin, et al.
Publicado: (2012)

OBHS Drives Abnormal Glycometabolis Reprogramming via GLUT1 in Breast Cancer
por: Wang, Kexin, et al.
Publicado: (2023)

Glucose transporters GLUT1, GLUT3, and GLUT4 have different effects on osteoblast proliferation and metabolism
por: Arponen, Milja, et al.
Publicado: (2022)

FoxM1 promotes epithelial-mesenchymal transition of hepatocellular carcinoma by targeting Snai1
por: Yu, Chun-Peng, et al.
Publicado: (2017)

FOXM1: Functional Roles of FOXM1 in Non-Malignant Diseases
por: Zhang, Zhenwang, et al.
Publicado: (2023)

Genetic determinants of FOXM1 overexpression in epithelial ovarian cancer and functional contribution to cell cycle progression
por: Barger, Carter J., et al.
Publicado: (2015)

ATAD2 expression increases [18F]Fluorodeoxyglucose uptake value in lung adenocarcinoma via AKT-GLUT1/HK2 pathway
por: Sun, Tong, et al.
Publicado: (2019)

Glucose Transporter Glut1-Dependent Metabolic Reprogramming Regulates Lipopolysaccharide-Induced Inflammation in RAW264.7 Macrophages
por: Cornwell, Alex, et al.
Publicado: (2023)

Foxm1 is essential for quiescence and maintenance of hematopoietic stem cells
por: Hou, Yu, et al.
Publicado: (2015)

Prolactin-induced Subcellular Targeting of GLUT1 Glucose Transporter in Living Mammary Epithelial Cells
por: Riskin, Arieh, et al.
Publicado: (2015)

The cell-penetrating FOXM1 N-terminus (M1-138) demonstrates potent inhibitory effects on cancer cells by targeting FOXM1 and FOXM1-interacting factor SMAD3
por: Zhang, Zhenwang, et al.
Publicado: (2019)

CPNE1 Enhances Colorectal Cancer Cell Growth, Glycolysis, and Drug Resistance Through Regulating the AKT-GLUT1/HK2 Pathway
por: Wang, Yuexia, et al.
Publicado: (2021)

Long noncoding RNA SLC2A1‐AS1 regulates aerobic glycolysis and progression in hepatocellular carcinoma via inhibiting the STAT3/FOXM1/GLUT1 pathway
por: Shang, Runze, et al.
Publicado: (2020)

BET Bromodomain Inhibition as a Therapeutic Strategy in Ovarian Cancer by Downregulating FoxM1
por: Zhang, Zhenfeng, et al.
Publicado: (2016)

High glucose causes developmental abnormalities in neuroepithelial cysts with actin and HK1 distribution changes
por: Peng, Sisi, et al.
Publicado: (2023)

Expression and functional characterization of FOXM1 in non-small cell lung cancer
por: Zhang, Yan, et al.
Publicado: (2018)

Glucose Metabolism Reprogramming in Bladder Cancer: Hexokinase 2 (HK2) as Prognostic Biomarker and Target for Bladder Cancer Therapy
por: Afonso, Julieta, et al.
Publicado: (2023)

HIV Protease Inhibitors Act as Competitive Inhibitors of the Cytoplasmic Glucose Binding Site of GLUTs with Differing Affinities for GLUT1 and GLUT4
por: Hresko, Richard C., et al.
Publicado: (2011)

Differential Expression of Glucose Transporter Proteins GLUT-1, GLUT-3, GLUT-8 and GLUT-12 in the Placenta of Macrosomic, Small-for-Gestational-Age and Growth-Restricted Foetuses
por: Stanirowski, Paweł Jan, et al.
Publicado: (2021)

Deletion of Glut1 in early postnatal cartilage reprograms chondrocytes toward enhanced glutamine oxidation
por: Wang, Cuicui, et al.
Publicado: (2021)

FoxM1 promotes breast tumorigenesis by activating PDGF-A and forming a positive feedback loop with the PDGF/AKT signaling pathway
por: Yu, Guanzhen, et al.
Publicado: (2015)

Deletion of GLUT1 and GLUT3 Reveals Multiple Roles for Glucose Metabolism in Platelet and Megakaryocyte Function
por: Fidler, Trevor P., et al.
Publicado: (2017)

FOXM1 expression is significantly associated with chemotherapy resistance and adverse prognosis in non-serous epithelial ovarian cancer patients
por: Tassi, Renata A., et al.
Publicado: (2017)

A novel FOXM1 isoform, FOXM1D, promotes epithelial–mesenchymal transition and metastasis through ROCKs activation in colorectal cancer
por: Zhang, X, et al.
Publicado: (2017)

Impact of pre-gestational and gestational diabetes mellitus on the expression of glucose transporters GLUT-1, GLUT-4 and GLUT-9 in human term placenta
por: Stanirowski, Paweł Jan, et al.
Publicado: (2016)

Molecular Dynamics Simulations of the Human Glucose Transporter GLUT1
por: Park, Min-Sun
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_imoqd35iimoo3mmkrhtfk3msla