Cargando…

Dual tumor suppressing and promoting function of Notch1 signaling in human prostate cancer

Adenocarcinomas of the prostate arise as multifocal heterogeneous lesions as the likely result of genetic and epigenetic alterations and deranged cell-cell communication. Notch signaling is an important form of intercellular communication with a role in growth/differentiation control and tumorigenes...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lefort, Karine, Ostano, Gian Paola, Mello-Grand, Maurizia, Calpini, Valérie, Scatolini, Maria, Farsetti, Antonella, Dotto, Gian Paolo, Chiorino, Giovanna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216996/ https://www.ncbi.nlm.nih.gov/pubmed/27384993 http://dx.doi.org/10.18632/oncotarget.10333

Ejemplares similares

Gene Expression Signature Predictive of Neuroendocrine Transformation in Prostate Adenocarcinoma
por: Ostano, Paola, et al.
Publicado: (2020)

HSD17B7 gene in self‐renewal and oncogenicity of keratinocytes from Black versus White populations
por: Xu, Xiaoying, et al.
Publicado: (2021)

Regulation of aromatase expression in breast cancer treated with anastrozole neoadjuvant therapy
por: GHIMENTI, CHIARA, et al.
Publicado: (2013)

Identification of a minimum number of genes to predict triple-negative breast cancer subgroups from gene expression profiles
por: Akhouayri, Laila, et al.
Publicado: (2022)

Androgen receptor is a determinant of melanoma targeted drug resistance
por: Samarkina, Anastasia, et al.
Publicado: (2023)

Overexpression of CD157 Contributes to Epithelial Ovarian Cancer Progression by Promoting Mesenchymal Differentiation
por: Morone, Simona, et al.
Publicado: (2012)

CYFIP1 is directly controlled by NOTCH1 and down-regulated in cutaneous squamous cell carcinoma
por: Dziunycz, Piotr J., et al.
Publicado: (2017)

ETS Transcription Factors Control Transcription of EZH2 and Epigenetic Silencing of the Tumor Suppressor Gene Nkx3.1 in Prostate Cancer
por: Kunderfranco, Paolo, et al.
Publicado: (2010)

Comprehensive Gene Expression Analysis to Identify Differences and Similarities between Sex- and Stage-Stratified Melanoma Samples
por: Chrysanthou, Eirini, et al.
Publicado: (2022)

Differential angiogenesis of bone and muscle endothelium in aging and inflammatory processes
por: Arrigoni, Chiara, et al.
Publicado: (2023)

A Novel Prostate Cell Type-Specific Gene Signature to Interrogate Prostate Tumor Differentiation Status and Monitor Therapeutic Response (Running Title: Phenotypic Classification of Prostate Tumors)
por: Mapelli, Sarah N., et al.
Publicado: (2020)

Epidermal Growth Factor Receptor (EGFR) mutation analysis, gene expression profiling and EGFR protein expression in primary prostate cancer
por: Peraldo-Neia, Caterina, et al.
Publicado: (2011)

Erratum: Mapelli, S.N., et al. A Novel Prostate Cell Type-Specific Gene Signature to Interrogate Prostate Tumor Differentiation Status and Monitor Therapeutic Response (Running Title: Phenotypic Classification of Prostate Tumors). Cancers 2020, 12, 176
por: Mapelli, Sarah N., et al.
Publicado: (2020)

Metabolic Reprogramming by Malat1 Depletion in Prostate Cancer
por: Nanni, Simona, et al.
Publicado: (2020)

NOTCH1 gene amplification promotes expansion of Cancer Associated Fibroblast populations in human skin
por: Katarkar, Atul, et al.
Publicado: (2020)

miR-34a/SIRT6 in squamous differentiation and cancer
por: Dotto, G Paolo, et al.
Publicado: (2014)

Two Novel Ceramide-Like Molecules and miR-5100 Levels as Biomarkers Improve Prediction of Prostate Cancer in Gray-Zone PSA
por: Mello-Grand, Maurizia, et al.
Publicado: (2021)

Gene and microRNA modulation upon trabectedin treatment in a human intrahepatic cholangiocarcinoma paired patient derived xenograft and cell line
por: Peraldo Neia, Caterina, et al.
Publicado: (2016)

Plasma microRNA ratios associated with breast cancer detection in a nested case–control study from a mammography screening cohort
por: Chiorino, Giovanna, et al.
Publicado: (2023)

Castration-Induced Downregulation of SPARC in Stromal Cells Drives Neuroendocrine Differentiation of Prostate Cancer
por: Enriquez, Claudia, et al.
Publicado: (2021)

Comparison of Microarray Platforms for Measuring Differential MicroRNA Expression in Paired Normal/Cancer Colon Tissues
por: Callari, Maurizio, et al.
Publicado: (2012)

Correction: Comparison of Microarray Platforms for Measuring Differential MicroRNA Expression in Paired Normal/Cancer Colon Tissues
por: Callari, Maurizio, et al.
Publicado: (2013)

Gender and sex—time to bridge the gap
por: Dotto, Gian‐Paolo
Publicado: (2019)

To be or not to be: The second law of thermodynamics and the flow of life and death
por: Dotto, Gian‐Paolo
Publicado: (2020)

Repurposing of the Antiepileptic Drug Levetiracetam to Restrain Neuroendocrine Prostate Cancer and Inhibit Mast Cell Support to Adenocarcinoma
por: Sulsenti, Roberta, et al.
Publicado: (2021)

Cells with stemness features are generated from in vitro transformed human fibroblasts
por: Bono, Bartolo, et al.
Publicado: (2018)

The Retinoid-Related Orphan Receptor RORα Promotes Keratinocyte Differentiation via FOXN1
por: Dai, Jun, et al.
Publicado: (2013)

Combined CSL and p53 downregulation promotes cancer-associated fibroblast activation
por: Procopio, Maria-Giuseppina, et al.
Publicado: (2015)

Differential Control of Notch1 Gene Transcription by Klf4 and Sp3 Transcription Factors in Normal versus Cancer-Derived Keratinocytes
por: Lambertini, Chiara, et al.
Publicado: (2010)

miR-181a decelerates proliferation in cutaneous squamous cell carcinoma by targeting the proto-oncogene KRAS
por: Neu, Johannes, et al.
Publicado: (2017)

Visualizing cellular heterogeneity by quantifying the dynamics of MAPK activity in live mammalian cells with synthetic fluorescent biosensors
por: Ma, Min, et al.
Publicado: (2020)

A Systems Biology Approach to Characterize the Regulatory Networks Leading to Trabectedin Resistance in an In Vitro Model of Myxoid Liposarcoma
por: Uboldi, Sarah, et al.
Publicado: (2012)

Calcineurin and ATF3: opposite roles in squamous skin cancer
por: Wu, Xunwei, et al.
Publicado: (2010)

The IKK/NF-κB signaling pathway requires Morgana to drive breast cancer metastasis
por: Fusella, Federica, et al.
Publicado: (2017)

Dualism of FGF and TGF-β Signaling in Heterogeneous Cancer-Associated Fibroblast Activation with ETV1 as a Critical Determinant
por: Bordignon, Pino, et al.
Publicado: (2019)

Class II phosphoinositide 3-kinase C2β regulates a novel signaling pathway involved in breast cancer progression
por: Chikh, Anissa, et al.
Publicado: (2016)

A promoter-proximal transcript targeted by genetic polymorphism controls E-cadherin silencing in human cancers
por: Pisignano, Giuseppina, et al.
Publicado: (2017)

The dual nature of Notch in tissue homeostasis and carcinogenesis
por: Valdez, Joseph M., et al.
Publicado: (2013)

Xeno-free cultured mesenchymal stromal cells release extracellular vesicles with a “therapeutic” miRNA cargo ameliorating cartilage inflammation in vitro
por: Palamà, Maria Elisabetta F., et al.
Publicado: (2023)

CPEB1 orchestrates a fine-tuning of miR-145-5p tumor-suppressive activity on TWIST1 translation in prostate cancer cells
por: Rajabi, Fatemeh, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_fr90eios0tqr9fff305o9f54pb