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The emergence of T790M mutation in EGFR-mutant lung adenocarcinoma patients having a history of acquired resistance to EGFR-TKI: focus on rebiopsy timing and long-term existence of T790M

Different growth kinetics occurring between the sensitive and T790M-containing cells may result in the repopulation of tumor cells over time. Little information has yet been uncovered on whether rebiopsy timing influences the T790M detection rate. We enrolled a total of 98 epidermal growth factor re...

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Detalles Bibliográficos
Autores principales: Tseng, Jeng-Sen, Su, Kang-Yi, Yang, Tsung-Ying, Chen, Kun-Chieh, Hsu, Kuo-Hsuan, Chen, Hsuan-Yu, Tsai, Chi-Ren, Yu, Sung-Liang, Chang, Gee-Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217000/
https://www.ncbi.nlm.nih.gov/pubmed/27384480
http://dx.doi.org/10.18632/oncotarget.10351