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AKT-induced PKM2 phosphorylation signals for IGF-1-stimulated cancer cell growth

Pyruvate kinase muscle type 2 (PKM2) exhibits post-translational modifications in response to various signals from the tumor microenvironment. Insulin-like growth factor 1 (IGF-1) is a crucial signal in the tumor microenvironment that promotes cell growth and survival in many human cancers. Herein,...

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Detalles Bibliográficos
Autores principales: Park, Young Soo, Kim, Dong Joon, Koo, Han, Jang, Se Hwan, You, Yeon-Mi, Cho, Jung Hee, Yang, Suk-Jin, Yu, Eun Sil, Jung, Yuri, Lee, Dong Chul, Kim, Jung-Ae, Park, Zee-Yong, Park, Kyung Chan, Yeom, Young Il
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217008/
https://www.ncbi.nlm.nih.gov/pubmed/27340866
http://dx.doi.org/10.18632/oncotarget.10179

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