The pancreatic niche inhibits the effectiveness of sunitinib treatment of pancreatic cancer

Current treatments for pancreatic ductal adenocarcinoma (PDA) are ineffective, making this the 4(th) leading cause of cancer deaths. Sunitinib is a broad-spectrum inhibitor of tyrosine kinase receptors mostly known for its anti-angiogenic effects. We tested the therapeutic effects of sunitinib in pa...

Descripción completa

Detalles Bibliográficos
Autores principales: Martínez-Bosch, Neus, Guerrero, Pedro Enrique, Moreno, Mireia, José, Anabel, Iglesias, Mar, Munné-Collado, Jessica, Anta, Héctor, Gibert, Joan, Orozco, Carlos Alberto, Vinaixa, Judith, Fillat, Cristina, Viñals, Francesc, Navarro, Pilar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217016/
https://www.ncbi.nlm.nih.gov/pubmed/27374084
http://dx.doi.org/10.18632/oncotarget.10199

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217016/
https://www.ncbi.nlm.nih.gov/pubmed/27374084
http://dx.doi.org/10.18632/oncotarget.10199

Ejemplares similares