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The pancreatic niche inhibits the effectiveness of sunitinib treatment of pancreatic cancer
Current treatments for pancreatic ductal adenocarcinoma (PDA) are ineffective, making this the 4(th) leading cause of cancer deaths. Sunitinib is a broad-spectrum inhibitor of tyrosine kinase receptors mostly known for its anti-angiogenic effects. We tested the therapeutic effects of sunitinib in pa...
Autores principales: | Martínez-Bosch, Neus, Guerrero, Pedro Enrique, Moreno, Mireia, José, Anabel, Iglesias, Mar, Munné-Collado, Jessica, Anta, Héctor, Gibert, Joan, Orozco, Carlos Alberto, Vinaixa, Judith, Fillat, Cristina, Viñals, Francesc, Navarro, Pilar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217016/ https://www.ncbi.nlm.nih.gov/pubmed/27374084 http://dx.doi.org/10.18632/oncotarget.10199 |
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