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Ubiquitin-specific protease 2 decreases p53-dependent apoptosis in cutaneous T-cell lymphoma

Treatment of advanced cutaneous T-cell lymphomas (CTCL) is challenging because they are resistant to conventional chemotherapy. USP2 has been shown to promote resistance to chemotherapeutic agents in several cancer models. We show here USP2 is expressed in quiescent and activated T-cells and its exp...

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Detalles Bibliográficos
Autores principales:	Wei, Tianling, Biskup, Edyta, Rahbek Gjerdrum, Lise Mette, Niazi, Omid, Ødum, Niels, Gniadecki, Robert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217025/ https://www.ncbi.nlm.nih.gov/pubmed/27351221 http://dx.doi.org/10.18632/oncotarget.10268

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