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miR-200b is a key regulator of tumor progression and metabolism targeting lactate dehydrogenase A in human malignant glioma
Lactate dehydrogenase A (LDHA) is involved in various cancers. In this study, we investigated the expression and function of LDHA in glioma. We found that LDHA was up-regulated in glioma samples. Furthermore, we found that overexpression of LDHA promoted proliferation, invasion and glycolysis in gli...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217028/ https://www.ncbi.nlm.nih.gov/pubmed/27374173 http://dx.doi.org/10.18632/oncotarget.10301 |