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IGF2-derived miR-483 mediated oncofunction by suppressing DLC-1 and associated with colorectal cancer

Emerging evidence indicates that IGF2 plays an important role in various human malignancies, including colorectal cancer (CRC). Hsa-miR-483 is located within intron 7 of the IGF2 locus. However, the mechanism by which increased IGF2 induces carcinogenesis remains largely elusive. DLC-1 has been iden...

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Detalles Bibliográficos
Autores principales:	Cui, Hengmi, Liu, Yuan, Jiang, Jingrui, Liu, Yangyang, Yang, Zhe, Wu, Shaogen, Cao, Wangsen, Cui, Isabelle H., Yu, Chenggong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217031/ https://www.ncbi.nlm.nih.gov/pubmed/27366946 http://dx.doi.org/10.18632/oncotarget.10309

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