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ΔNp63 mediates cellular survival and metastasis in canine osteosarcoma

p63 is a structural homolog within the 53 family encoding two isoforms, ΔNp63 and TAp63. The oncogenic activity of ΔNp63 has been demonstrated in multiple cancers, however the underlying mechanisms that contribute to tumorigenesis are poorly characterized. Osteosarcoma (OSA) is the most common prima...

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Detalles Bibliográficos
Autores principales: Cam, Maren, Gardner, Heather L., Roberts, Ryan D., Fenger, Joelle M., Guttridge, Denis C., London, Cheryl A., Cam, Hakan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217036/
https://www.ncbi.nlm.nih.gov/pubmed/27391430
http://dx.doi.org/10.18632/oncotarget.10406