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The insulin-like growth factor system in multiple myeloma: diagnostic and therapeutic potential
Multiple myeloma (MM) is a highly heterogeneous plasma cell malignancy. The MM cells reside in the bone marrow (BM), where reciprocal interactions with the BM niche foster MM cell survival, proliferation, and drug resistance. As in most cancers, the insulin-like growth factor (IGF) system has been d...
Autores principales: | Bieghs, Liesbeth, Johnsen, Hans E., Maes, Ken, Menu, Eline, Van Valckenborgh, Els, Overgaard, Michael T., Nyegaard, Mette, Conover, Cheryl A., Vanderkerken, Karin, De Bruyne, Elke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217049/ https://www.ncbi.nlm.nih.gov/pubmed/27129151 http://dx.doi.org/10.18632/oncotarget.8982 |
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