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Structural identifiability of equilibrium ligand-binding parameters
Understanding the interactions of proteins with their ligands requires knowledge of molecular properties, such as binding site affinities and the effects that binding at one site exerts on binding at other sites (cooperativity). These properties cannot be measured directly and are usually estimated...
Autores principales: | Middendorf, Thomas R., Aldrich, Richard W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217090/ https://www.ncbi.nlm.nih.gov/pubmed/27993952 http://dx.doi.org/10.1085/jgp.201611702 |
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