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CRISPR/Cas9-Induced Double-Strand Break Repair in Arabidopsis Nonhomologous End-Joining Mutants
Double-strand breaks (DSBs) are one of the most harmful DNA lesions. Cells utilize two main pathways for DSB repair: homologous recombination (HR) and nonhomologous end-joining (NHEJ). NHEJ can be subdivided into the KU-dependent classical NHEJ (c-NHEJ) and the more error-prone KU-independent backup...
Autores principales: | Shen, Hexi, Strunks, Gary D., Klemann, Bart J. P. M., Hooykaas, Paul J. J., de Pater, Sylvia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217109/ https://www.ncbi.nlm.nih.gov/pubmed/27866150 http://dx.doi.org/10.1534/g3.116.035204 |
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