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Dissecting Gene Expression Changes Accompanying a Ploidy-Based Phenotypic Switch

Aneuploidy, a state in which the chromosome number deviates from a multiple of the haploid count, significantly impacts human health. The phenotypic consequences of aneuploidy are believed to arise from gene expression changes associated with the altered copy number of genes on the aneuploid chromos...

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Detalles Bibliográficos
Autores principales: Cromie, Gareth A., Tan, Zhihao, Hays, Michelle, Jeffery, Eric W., Dudley, Aimée M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217112/
https://www.ncbi.nlm.nih.gov/pubmed/27836908
http://dx.doi.org/10.1534/g3.116.036160