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Multiplex shRNA Screening of Germ Cell Development by in Vivo Transfection of Mouse Testis
Spermatozoa are one of the few mammalian cell types that cannot be fully derived in vitro, severely limiting the application of modern genomic techniques to study germ cell biology. The current gold standard approach of characterizing single-gene knockout mice is slow as generation of each mutant li...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Genetics Society of America
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217113/ https://www.ncbi.nlm.nih.gov/pubmed/27856695 http://dx.doi.org/10.1534/g3.116.036087 |