Protein kinase C inhibitor Gö6976 but not Gö6983 induces the reversion of E- to N-cadherin switch and metastatic phenotype in melanoma: identification of the role of protein kinase D1

BACKGROUND: Melanoma is a highly metastatic type of cancer that is resistant to all standard anticancer therapies and thus has a poor prognosis. Therefore, metastatic melanoma represents a significant clinical problem and requires novel and effective targeted therapies. The protein kinase C (PKC) fa...

Descripción completa

Detalles Bibliográficos
Autores principales: Merzoug-Larabi, Messaouda, Spasojevic, Caroline, Eymard, Marianne, Hugonin, Caroline, Auclair, Christian, Karam, Manale
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217271/
https://www.ncbi.nlm.nih.gov/pubmed/28056869
http://dx.doi.org/10.1186/s12885-016-3007-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217271/
https://www.ncbi.nlm.nih.gov/pubmed/28056869
http://dx.doi.org/10.1186/s12885-016-3007-5

Ejemplares similares