Aldose reductase mediates endothelial cell dysfunction induced by high uric acid concentrations

BACKGROUND: Uric acid (UA) is an antioxidant found in human serum. However, high UA levels may also have pro-oxidant functions. According to previous research, aldose reductase (AR) plays a vital role in the oxidative stress-related complications of diabetes. We sought to determine the mechanism by...

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Detalles Bibliográficos
Autores principales: Huang, Zhiyong, Hong, Quan, Zhang, Xueguang, Xiao, Wenzhen, Wang, Liyuan, Cui, Shaoyuan, Feng, Zhe, Lv, Yang, Cai, Guangyan, Chen, Xiangmei, Wu, Di
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217275/
https://www.ncbi.nlm.nih.gov/pubmed/28057038
http://dx.doi.org/10.1186/s12964-016-0158-6

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