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Effects of passiflora incarnata and midazolam for control of anxiety in patients undergoing dental extraction
BACKGROUND: Anxiety symptoms are frequently observed in dental patients, whether they are undergoing simple or more invasive procedures such as surgery. This research aimed to compare the effects of Passiflora incarnata and midazolam for the control of anxiety in patients undergoing mandibular third...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medicina Oral S.L.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217504/ https://www.ncbi.nlm.nih.gov/pubmed/27918731 http://dx.doi.org/10.4317/medoral.21140 |
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author | Dantas, Liliane-Poconé de Oliveira-Ribeiro, Artur de Almeida-Souza, Liane-Maciel Groppo, Francisco-Carlos |
author_facet | Dantas, Liliane-Poconé de Oliveira-Ribeiro, Artur de Almeida-Souza, Liane-Maciel Groppo, Francisco-Carlos |
author_sort | Dantas, Liliane-Poconé |
collection | PubMed |
description | BACKGROUND: Anxiety symptoms are frequently observed in dental patients, whether they are undergoing simple or more invasive procedures such as surgery. This research aimed to compare the effects of Passiflora incarnata and midazolam for the control of anxiety in patients undergoing mandibular third molar extraction. MATERIAL AND METHODS: Forty volunteers underwent bilateral extraction of their mandibular third molars in a randomized, controlled, double-blind, crossover clinical trial. Passiflora incarnata (260 mg) or midazolam (15 mg) were orally administered 30 minutes before surgery. The anxiety level of participants was evaluated by questionnaires and measurement of physical parameters, including heart rate (HR), blood pressure (BP), and oxygen saturation (SpO2). RESULTS: Considering each procedure independently, there were no significant differences between the protocols in BP, HR, and SpO2. Over 70% of the volunteers responded that they felt quiet or a little anxious under both protocols. With midazolam, 20% of the participants reported amnesia (not remembering anything at all), while Passiflora showed little or no ability to interfere with memory formation. CONCLUSIONS: Passiflora incarnata showed an anxiolytic effect similar to midazolam, and was safe and effective for conscious sedation in adult patients who underwent extraction of their mandibular third molars. Key words:Passiflora incarnata, midazolam, anxiety, oral surgery. |
format | Online Article Text |
id | pubmed-5217504 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Medicina Oral S.L. |
record_format | MEDLINE/PubMed |
spelling | pubmed-52175042017-01-09 Effects of passiflora incarnata and midazolam for control of anxiety in patients undergoing dental extraction Dantas, Liliane-Poconé de Oliveira-Ribeiro, Artur de Almeida-Souza, Liane-Maciel Groppo, Francisco-Carlos Med Oral Patol Oral Cir Bucal Research BACKGROUND: Anxiety symptoms are frequently observed in dental patients, whether they are undergoing simple or more invasive procedures such as surgery. This research aimed to compare the effects of Passiflora incarnata and midazolam for the control of anxiety in patients undergoing mandibular third molar extraction. MATERIAL AND METHODS: Forty volunteers underwent bilateral extraction of their mandibular third molars in a randomized, controlled, double-blind, crossover clinical trial. Passiflora incarnata (260 mg) or midazolam (15 mg) were orally administered 30 minutes before surgery. The anxiety level of participants was evaluated by questionnaires and measurement of physical parameters, including heart rate (HR), blood pressure (BP), and oxygen saturation (SpO2). RESULTS: Considering each procedure independently, there were no significant differences between the protocols in BP, HR, and SpO2. Over 70% of the volunteers responded that they felt quiet or a little anxious under both protocols. With midazolam, 20% of the participants reported amnesia (not remembering anything at all), while Passiflora showed little or no ability to interfere with memory formation. CONCLUSIONS: Passiflora incarnata showed an anxiolytic effect similar to midazolam, and was safe and effective for conscious sedation in adult patients who underwent extraction of their mandibular third molars. Key words:Passiflora incarnata, midazolam, anxiety, oral surgery. Medicina Oral S.L. 2017-01 2016-12-06 /pmc/articles/PMC5217504/ /pubmed/27918731 http://dx.doi.org/10.4317/medoral.21140 Text en Copyright: © 2017 Medicina Oral S.L. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Dantas, Liliane-Poconé de Oliveira-Ribeiro, Artur de Almeida-Souza, Liane-Maciel Groppo, Francisco-Carlos Effects of passiflora incarnata and midazolam for control of anxiety in patients undergoing dental extraction |
title | Effects of passiflora incarnata and midazolam for control
of anxiety in patients undergoing dental extraction |
title_full | Effects of passiflora incarnata and midazolam for control
of anxiety in patients undergoing dental extraction |
title_fullStr | Effects of passiflora incarnata and midazolam for control
of anxiety in patients undergoing dental extraction |
title_full_unstemmed | Effects of passiflora incarnata and midazolam for control
of anxiety in patients undergoing dental extraction |
title_short | Effects of passiflora incarnata and midazolam for control
of anxiety in patients undergoing dental extraction |
title_sort | effects of passiflora incarnata and midazolam for control
of anxiety in patients undergoing dental extraction |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217504/ https://www.ncbi.nlm.nih.gov/pubmed/27918731 http://dx.doi.org/10.4317/medoral.21140 |
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