Gastroesophageal junction adenocarcinoma displays abnormalities in homologous recombination and nucleotide excision repair

OBJECTIVE: Esophageal adenocarcinoma (EAC) continues to be a disease associated with high mortality. Among the factors leading to poor outcomes are innate resistance to currently available therapies, advanced stage at diagnosis, and complex biology. Platinum and ionizing radiation form the backbone...

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Detalles Bibliográficos
Autores principales: Dewalt, Robin I, Kesler, Kenneth A, Hammoud, Zane T, Baldridge, LeeAnn, Hattab, Eyas M, Jalal, Shadia I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217507/
https://www.ncbi.nlm.nih.gov/pubmed/28210138
http://dx.doi.org/10.2147/LCTT.S57594

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