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AXL receptor tyrosine kinase as a therapeutic target in NSCLC
The AXL receptor tyrosine kinase and its ligand, Gas6, regulate key processes in lung cancer growth, metastasis, and epithelial–mesenchymal transition-associated drug resistance. Gas6 and AXL expression have been correlated with poor prognosis and advanced clinical stage in patients with lung cancer...
Autores principales: | Okimoto, Ross A, Bivona, Trever G |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217513/ https://www.ncbi.nlm.nih.gov/pubmed/28210148 http://dx.doi.org/10.2147/LCTT.S60438 |
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