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Profile of bavituximab and its potential in the treatment of non-small-cell lung cancer
Bavituximab is a an unconjugated, chimeric immunoglobulin G1 (IgG1) monoclonal antibody directed against the phosphatidylserine (PS) expressed on tumor endothelium, with a specific mechanism of action. PS is an anionic membrane phospholipid, physiologically restricted to the internal membrane leafle...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Dove Medical Press
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217514/ https://www.ncbi.nlm.nih.gov/pubmed/28210141 http://dx.doi.org/10.2147/LCTT.S37981 |