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Profile of bavituximab and its potential in the treatment of non-small-cell lung cancer

Bavituximab is a an unconjugated, chimeric immunoglobulin G1 (IgG1) monoclonal antibody directed against the phosphatidylserine (PS) expressed on tumor endothelium, with a specific mechanism of action. PS is an anionic membrane phospholipid, physiologically restricted to the internal membrane leafle...

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Detalles Bibliográficos
Autores principales:	Stasi, Irene, Cappuzzo, Federico
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2014
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217514/ https://www.ncbi.nlm.nih.gov/pubmed/28210141 http://dx.doi.org/10.2147/LCTT.S37981

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