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Growth, progression and chromosome instability of Neuroblastoma: a new scenario of tumorigenesis?
BACKGROUND: Neuroblastoma is a pediatric cancer with a low survival rate of patients with metastatic stage 4 disease. Tumor aggressiveness and progression have been associated with structural copy number variations (CNVs) that are observed in malignant cells. In contrast, localized Neuroblastomas, w...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217541/ https://www.ncbi.nlm.nih.gov/pubmed/28056863 http://dx.doi.org/10.1186/s12885-016-2986-6 |