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Cocktail treatment with EGFR-specific and CD133-specific chimeric antigen receptor-modified T cells in a patient with advanced cholangiocarcinoma

BACKGROUND: Cholangiocarcinoma (CCA) is one of the most fatal malignant tumors with increasing incidence, mortality, and insensitivity to traditional chemo-radiotherapy and targeted therapy. Chimeric antigen receptor-modified T cell (CART) immunotherapy represents a novel strategy for the management...

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Detalles Bibliográficos
Autores principales:	Feng, Kai-chao, Guo, Ye-lei, Liu, Yang, Dai, Han-ren, Wang, Yao, Lv, Hai-yan, Huang, Jian-hua, Yang, Qing-ming, Han, Wei-dong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Case Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217546/ https://www.ncbi.nlm.nih.gov/pubmed/28057014 http://dx.doi.org/10.1186/s13045-016-0378-7

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