Acriflavine Inhibits Acquired Drug Resistance by Blocking the Epithelial-to-Mesenchymal Transition and the Unfolded Protein Response

Epithelial-to-mesenchymal transition (EMT) is linked to tumor invasion, drug resistance and aggressive disease and this is largely dependent on the cell's microenvironment. Acriflavine (ACF) is an old antibacterial drug recently also suggested as anticancer agent and HIF inhibitor. We wanted to...

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Detalles Bibliográficos
Autores principales: Dekervel, Jeroen, Bulle, Ashenafi, Windmolders, Petra, Lambrechts, Diether, Van Cutsem, Eric, Verslype, Chris, van Pelt, Jos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2016
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217771/
https://www.ncbi.nlm.nih.gov/pubmed/27987431
http://dx.doi.org/10.1016/j.tranon.2016.11.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217771/
https://www.ncbi.nlm.nih.gov/pubmed/27987431
http://dx.doi.org/10.1016/j.tranon.2016.11.008

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