Proteome Profiling Outperforms Transcriptome Profiling for Coexpression Based Gene Function Prediction

Coexpression of mRNAs under multiple conditions is commonly used to infer cofunctionality of their gene products despite well-known limitations of this “guilt-by-association” (GBA) approach. Recent advancements in mass spectrometry-based proteomic technologies have enabled global expression profilin...

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Detalles Bibliográficos
Autores principales: Wang, Jing, Ma, Zihao, Carr, Steven A., Mertins, Philipp, Zhang, Hui, Zhang, Zhen, Chan, Daniel W., Ellis, Matthew J. C., Townsend, R. Reid, Smith, Richard D., McDermott, Jason E., Chen, Xian, Paulovich, Amanda G., Boja, Emily S., Mesri, Mehdi, Kinsinger, Christopher R., Rodriguez, Henry, Rodland, Karin D., Liebler, Daniel C., Zhang, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217778/
https://www.ncbi.nlm.nih.gov/pubmed/27836980
http://dx.doi.org/10.1074/mcp.M116.060301

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