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Depleted aldehyde dehydrogenase 1A1 (ALDH1A1) reverses cisplatin resistance of human lung adenocarcinoma cell A549/DDP

BACKGROUND: Cisplatin is the standard first‐line chemotherapeutic agent for the treatment of non‐small cell lung cancer (NSCLC). However, resistance to chemotherapy has been a major obstacle in the management of NSCLC. Aldehyde dehydrogenase 1A1 (ALDH1A1) overexpression has been observed in a variet...

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Detalles Bibliográficos
Autores principales:	Wei, Yunyan, Wu, Shuangshuang, Xu, Wei, Liang, Yan, Li, Yue, Zhao, Weihong, Wu, Jianqing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons Australia, Ltd 2016
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217899/ https://www.ncbi.nlm.nih.gov/pubmed/27813328 http://dx.doi.org/10.1111/1759-7714.12400

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