Positioning of Tacrolimus for the Treatment of Diabetic Nephropathy Based on Computational Network Analysis

OBJECTIVE: To evaluate tacrolimus as therapeutic option for diabetic nephropathy (DN) based on molecular profile and network-based molecular model comparisons. MATERIALS AND METHODS: We generated molecular models representing pathophysiological mechanisms of DN and tacrolimus mechanism of action (Mo...

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Detalles Bibliográficos
Autores principales: Aschauer, Constantin, Perco, Paul, Heinzel, Andreas, Sunzenauer, Judith, Oberbauer, Rainer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217951/
https://www.ncbi.nlm.nih.gov/pubmed/28060893
http://dx.doi.org/10.1371/journal.pone.0169518

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217951/
https://www.ncbi.nlm.nih.gov/pubmed/28060893
http://dx.doi.org/10.1371/journal.pone.0169518

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