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Positioning of Tacrolimus for the Treatment of Diabetic Nephropathy Based on Computational Network Analysis
OBJECTIVE: To evaluate tacrolimus as therapeutic option for diabetic nephropathy (DN) based on molecular profile and network-based molecular model comparisons. MATERIALS AND METHODS: We generated molecular models representing pathophysiological mechanisms of DN and tacrolimus mechanism of action (Mo...
Autores principales: | Aschauer, Constantin, Perco, Paul, Heinzel, Andreas, Sunzenauer, Judith, Oberbauer, Rainer |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217951/ https://www.ncbi.nlm.nih.gov/pubmed/28060893 http://dx.doi.org/10.1371/journal.pone.0169518 |
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